4-[(E)-2-(3-fluorophenyl)-1-phenylethenyl]phenol

Names

[ CAS No. ]:
299-08-1

[ Name ]:
4-[(E)-2-(3-fluorophenyl)-1-phenylethenyl]phenol

[Synonym ]:
1-<3-Fluor-phenyl<-2-<4-hydroxy-phenyl>-2-phenyl-aethylen

Chemical & Physical Properties

[ Density]:
1.201g/cm3

[ Boiling Point ]:
397.2ºC at 760mmHg

[ Molecular Formula ]:
C20H15FO

[ Molecular Weight ]:
290.33100

[ Flash Point ]:
248.2ºC

[ Exact Mass ]:
290.11100

[ PSA ]:
20.23000

[ LogP ]:
5.12020

[ Vapour Pressure ]:
7.07E-07mmHg at 25°C

[ Index of Refraction ]:
1.653

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SL4585000
CHEMICAL NAME :
Phenol, p-(m-fluoro-alpha-phenylstyryl)-
CAS REGISTRY NUMBER :
299-08-1
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C20-H15-F-O
MOLECULAR WEIGHT :
290.35
WISWESSER LINE NOTATION :
QR DYR&U1R CF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
500 mg/kg
SEX/DURATION :
male 10 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 151,475,1964
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
3 mg/kg
SEX/DURATION :
female 3 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - uterus, cervix, vagina
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 151,475,1964

Synthetic Route

Precursor & DownStream


Related Compounds