5-Methoxy-2-thiouridine

Names

[ CAS No. ]:
30771-43-8

[ Name ]:
5-Methoxy-2-thiouridine

[Synonym ]:
Uridine,5-methoxy-2-thio

Biological Activity

[Description]:

5-Methoxy-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C10H14N2O6S

[ Molecular Weight ]:
290.29

[ Exact Mass ]:
290.05700

[ PSA ]:
149.29000

Related Compounds