Antitrypanosomal agent 8

Names

[ CAS No. ]:
332376-42-8

[ Name ]:
Antitrypanosomal agent 8

Biological Activity

[Description]:

Antitrypanosomal agent 8 (compound 3b) has potent antitrypanosomal activity against Trypanosoma brucei with an IC50 value of 0.79 μM and exhibits certain cytotoxicity in L6 cells (IC50=80.95 μM)[1].

[Related Catalog]:

Research Areas >> Infection

[Target]

IC50: 0.79 μM (Trypanosoma brucei)[1]


[References]

[1]. Shaykoon MS, et al. Design, synthesis and antitrypanosomal activity of heteroaryl-based 1,2,4-triazole and 1,3,4-oxadiazole derivatives. Bioorg Chem. 2020 Jul;100:103933.

Chemical & Physical Properties

[ Molecular Formula ]:
C23H19N5O2S

[ Molecular Weight ]:
429.49

Related Compounds