α-Hydroxytriazolam
Names
[ CAS No. ]:
37115-45-0
[ Name ]:
α-Hydroxytriazolam
[Synonym ]:
MFCD00467159
[8-chloro-6-(2-chlorophenyl)-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-1-yl]methanol
Chemical & Physical Properties
[ Melting Point ]:
239-241℃
[ Molecular Formula ]:
C17H12Cl2N4O
[ Molecular Weight ]:
359.20900
[ Flash Point ]:
9℃
[ Exact Mass ]:
358.03900
[ PSA ]:
63.30000
[ LogP ]:
2.85300
[ Storage condition ]:
Controlled Substance, -20°C Freezer
MSDS
Safety Information
[ Symbol ]:
GHS02, GHS06, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H225-H301 + H311 + H331-H370
[ Precautionary Statements ]:
P210-P260-P280-P301 + P310-P311
[ Personal Protective Equipment ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
20/21/22-63
[ Safety Phrases ]:
22-36
[ RIDADR ]:
UN1230 - class 3 - PG 2 - Methanol, solution
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Methods Mol. Biol. 603 , 89-105, (2010)
We describe a single method for the detection and quantitation of 13 commonly prescribed benzodiazepines and metabolites: alpha-hydroxyalprazolam, alpha-hydroxyethylflurazepam, alpha-hydroxytriazolam,...
Quantitation of benzodiazepines in blood and urine using gas chromatography-mass spectrometry (GC-MS).Methods Mol. Biol. 603 , 75-87, (2010)
The benzodiazepine assay utilizes gas chromatography-mass spectrometry (GC-MS) for the analysis of diazepam, nordiazepam, oxazepam, temazepam, lorazepam, alpha-hydroxyalprazolam, and alpha-hydroxytria...
Sensitive UPLC-MS-MS assay for 21 benzodiazepine drugs and metabolites, zolpidem and zopiclone in serum or plasma.J. Anal. Toxicol. 36(7) , 472-6, (2012)
This paper reports an ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS-MS) method to quantitate 21 benzodiazepines, zolpidem and zopiclone in serum and plasma. After liquid-li...