2-(2,6-dimethylanilino)pyridine-3-carboxylic acid
Names
[ CAS No. ]:
4394-04-1
[ Name ]:
2-(2,6-dimethylanilino)pyridine-3-carboxylic acid
[Synonym ]:
Metanixin
2-(2',6'-Dimethylphenylamin)-3-pyridincarboxylsaeure
2-[(2,6-dimethylphenyl)amino]pyridine-3-carboxylic acid
Acido nixilico
2-(2,6-xylidino)-nicotinic acid
Acidum nixylicum
Metanixine [INN-French]
Metanixino [Spanish]
2-(2,6-dimethyl-anilino)-nicotinic acid
2-(2,6-Dimethyl-anilino)-nicotinsaeure
Metanixinum [Latin]
Metanixinum [INN-Latin]
Metanixino [INN-Spanish]
Metanixine [French]
Acide nixylique
Chemical & Physical Properties
[ Density]:
1.25 g/cm3
[ Boiling Point ]:
393.972ºC at 760mmHg
[ Molecular Formula ]:
C14H14N2O2
[ Molecular Weight ]:
242.27300
[ Flash Point ]:
192.068ºC
[ Exact Mass ]:
242.10600
[ PSA ]:
62.22000
[ LogP ]:
3.21320
[ Index of Refraction ]:
1.646
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QT2999350
- CHEMICAL NAME :
- Nicotinic acid, 2-(2,3-xylidino)-
- CAS REGISTRY NUMBER :
- 4394-04-1
- BEILSTEIN REFERENCE NO. :
- 0482454
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C14-H14-N2-O2
- MOLECULAR WEIGHT :
- 242.30
- WISWESSER LINE NOTATION :
- T6NJ BMR B1 C1& CVQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2300 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 22,157,1967
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 645 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 22,157,1967
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 385 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 22,157,1967
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 280 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 22,157,1967
Safety Information
[ HS Code ]:
2933399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933399090
[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%