Acetyl-(N-Me-Leu17,N-Me-Phe19)-Amyloid β-Protein (16-20) amide trifluoroacetate salt
Names
[ CAS No. ]:
461640-33-5
[ Name ]:
Acetyl-(N-Me-Leu17,N-Me-Phe19)-Amyloid β-Protein (16-20) amide trifluoroacetate salt
[Synonym ]:
A|A16-20m
Ac-Lys-(Me)Leu-Val-(Me)Phe-Phe-NH2 trifluoroacetate salt
Chemical & Physical Properties
[ Molecular Formula ]:
C41H60F3N7O8
[ Molecular Weight ]:
835.95200
[ Exact Mass ]:
835.44600
[ PSA ]:
245.79000
[ LogP ]:
6.92070
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
Articles
J. Pept. Res. 60 , 37-55, (2002)
Alzheimer's disease, Huntington's disease and prion diseases are part of a growing list of diseases associated with formation of beta-sheet containing fibrils. In a previous publication, we demonstrat...
Probing the role of backbone hydrogen bonding in beta-amyloid fibrils with inhibitor peptides containing ester bonds at alternate positions.Biochemistry 42 , 475-485, (2003)
Protein-protein interactions are frequently mediated by stable, intermolecular beta-sheets. A number of cytokines and the HIV Protease, for example, dimerize through beta-sheet motifs. Evidence also s...