N-Acetyl-D-glucosamine-15N

Names

[ CAS No. ]:
478518-85-3

[ Name ]:
N-Acetyl-D-glucosamine-15N

Biological Activity

[Description]:

N-Acetyl-D-glucosamine-15N is the 15N labeled N-Acetyl-D-glucosamine. N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose) is a monosaccharide derivative of gluc[1][2].

[Related Catalog]:

Research Areas >> Metabolic Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. Slawson C, et al. O-GlcNAc cycling: how a single sugar post-translational modification is changing the way we think about signaling networks. J Cell Biochem. 2006 Jan 1;97(1):71-83.

Chemical & Physical Properties

[ Molecular Formula ]:
C8H15NO6

[ Molecular Weight ]:
222.20100

[ Exact Mass ]:
222.08700

[ PSA ]:
119.25000

Related Compounds