F3226-1387

Names

[ CAS No. ]:
618877-25-1

[ Name ]:
F3226-1387

Biological Activity

[Description]:

F3226-1387 is a potent Entamoeba histolytica O-acetylserine sulfhydrylase EhOASS3 inhibitor with an IC50 value of 38 μM. F3226-1387 can suppress the growth of the amoeba[1].

[Related Catalog]:

Research Areas >> Infection

[Target]

IC50: 38 μM (EhOASS3)[1]


[References]

[1]. Dharavath S, et al. Crystal structure of O-Acetylserine sulfhydralase (OASS) isoform 3 from Entamoeba histolytica: Pharmacophore-based virtual screening and validation of novel inhibitors. Eur J Med Chem. 2020 Apr 15;192:112157.

Chemical & Physical Properties

[ Molecular Formula ]:
C23H15ClN2O5

[ Molecular Weight ]:
434.83

Related Compounds