Tiglyl carnitine

Names

[ CAS No. ]:
64681-36-3

[ Name ]:
Tiglyl carnitine

[Synonym ]:
1-Propanaminium, 3-carboxy-N,N,N-trimethyl-2-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]oxy]-, inner salt, (2R)-
O-tiglyl-L-carnitine
(3R)-3-{[(2E)-2-Methyl-2-butenoyl]oxy}-4-(trimethylammonio)butanoate

Biological Activity

[Description]:

Tiglyl carnitine is found to be associated with celiac disease and mitochondrial acetoacetyl-CoA thiolase (T2) deficiency.

[Related Catalog]:

Research Areas >> Metabolic Disease
Natural Products >> Others

[Target]

Human Endogenous Metabolite


[References]

[1]. Fukao T, et al. The mitochondrial acetoacetyl-CoA thiolase (T2) deficiency in Japanese patients: urinary organic acid and blood acylcarnitine profiles under stable conditions have subtle abnormalities in T2-deficient patients with some residual T2 activity. J Inherit Metab Dis. 2003;26(5):423-31.


[Related Small Molecules]

3-Methyladenine | Hydrocortisone | Acetylcysteine(N-acetylcysteine) | Retinoic acid | Melatonine | Dinoprostone | Nicotinamide | Adenosine triphosphate | 4-Acetamidophenol | Prostaglandin E1 | Dehydroepiandrosterone | Corticosterone | Progesterone | Docosahexaenoic Acid | NAD+

Chemical & Physical Properties

[ Molecular Formula ]:
C12H21NO4

[ Molecular Weight ]:
243.299

[ Exact Mass ]:
243.147064

[ LogP ]:
-2.80

[ Storage condition ]:
2-8℃

Related Compounds