Factor V Activating Enzyme

No Any Chemical & Physical Properties

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Structural basis of thrombin-mediated factor V activation: the Glu666-Glu672 sequence is critical for processing at the heavy chain-B domain junction.

Blood 117(26) , 7164-73, (2011)

Thrombin-catalyzed activation of coagulation factor V (FV) is an essential positive feedback reaction within the blood clotting system. Efficient processing at the N- (Arg(709)-Ser(710)) and C-termina...

Phosphatidylserine-induced factor Xa dimerization and binding to factor Va are competing processes in solution.

Biochemistry 52(1) , 143-51, (2013)

A soluble, short chain phosphatidylserine, 1,2-dicaproyl-sn-glycero-3-phospho-l-serine (C6PS), binds to discrete sites on FXa, FVa, and prothrombin to alter their conformations, to promote FXa dimeriz...

Modulation of prothrombinase assembly and activity by phosphatidylethanolamine.

J. Biol. Chem. 286(41) , 35535-42, (2011)

Constituents of platelet membranes regulate the activity of the prothrombinase complex. We demonstrate that membranes containing phosphatidylcholine and phosphatidylethanolamine (PE) bind factor Va wi...

More Articles