diethyl-[2-[(2-heptoxyphenyl)carbamoyloxy]propyl]azanium,chloride

Names

[ CAS No. ]:
68931-03-3

[ Name ]:
diethyl-[2-[(2-heptoxyphenyl)carbamoyloxy]propyl]azanium,chloride

[Synonym ]:
carbisocaine chloride
Carbisocaine hydrochloride
karbisokaine
Carbisocaine
Carbizocaine hydrochloride
BK-95

Chemical & Physical Properties

[ Boiling Point ]:
434.7ºC at 760 mmHg

[ Molecular Formula ]:
C21H37ClN2O3

[ Molecular Weight ]:
400.98300

[ Flash Point ]:
216.7ºC

[ Exact Mass ]:
400.24900

[ PSA ]:
54.29000

[ LogP ]:
6.13020

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
FD8940400
CHEMICAL NAME :
Carbanilic acid, o-(heptyloxy)-, 2-(diethylamino)-1-methylethyl ester, hydrochloride
CAS REGISTRY NUMBER :
68931-03-3
LAST UPDATED :
199406
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C21-H36-N2-O3.Cl-H
MOLECULAR WEIGHT :
401.05

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
63 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DECRDP Drugs under Experimental and Clinical Research. (Bioscience Ediprint, Blvd. James-Fazy 13, 1201 Geneva 1, Switzerland) V.1- 1977- Volume(issue)/page/year: 12,845,1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
380 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DECRDP Drugs under Experimental and Clinical Research. (Bioscience Ediprint, Blvd. James-Fazy 13, 1201 Geneva 1, Switzerland) V.1- 1977- Volume(issue)/page/year: 12,845,1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
16 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DECRDP Drugs under Experimental and Clinical Research. (Bioscience Ediprint, Blvd. James-Fazy 13, 1201 Geneva 1, Switzerland) V.1- 1977- Volume(issue)/page/year: 12,845,1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
48 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DMDIEQ Drug Metabolism and Drug Interactions. (Freund Publishing House, Suite 500, Chesham House, 150 Regent Street, London, W1R 5FA, United Kingdom) V.6- 1988- Volume(issue)/page/year: 9,321,1991
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CKFRAY Ceskoslovenska Farmacie. (PNS-Ustredni Expedice a Dovoz Tisku, Kafkova 19, 160 00 Prague 6, Czechoslovakia) V.1- 1952- Volume(issue)/page/year: 27,167,1978

Related Compounds