L-Phenylalanine,Indole-15N

Names

[ CAS No. ]:
84344-22-9

[ Name ]:
L-Phenylalanine,Indole-15N

[Synonym ]:
(S)-tryptophan-indole-(15)N
L-TRYPTOPHAN (INDOLE-15N)
L-(15Nindole)tryptophan
L-<1'-(15N)>tryptophan
<15NεI>-tryptophan

Biological Activity

[Description]:

L-Phenylalanine,Indole-15N is the 15N labeled L-Tryptophan[1]. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[2].

[Related Catalog]:

Research Areas >> Cancer
Research Areas >> Metabolic Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Slominski A, et al. Conversion of L-tryptophan to serotonin and melatonin in human melanoma cells. FEBS Lett. 2002 Jan 30;511(1-3):102-6.  

Chemical & Physical Properties

[ Molecular Formula ]:
C11H12N2O2

[ Molecular Weight ]:
205.21900

[ Exact Mass ]:
205.08700

[ PSA ]:
79.11000

[ LogP ]:
1.82260

Related Compounds