Dodecanedioic acid-d4

Names

[ CAS No. ]:
97543-02-7

[ Name ]:
Dodecanedioic acid-d4

Biological Activity

[Description]:

Dodecanedioic acid-d4 is the deuterium labeled Dodecanedioic acid[1]. Dodecanedioic acid (C12) is a dicarboxylic acid with a metabolic pathway intermediate to those of lipids and carbohydrates[2].

[Related Catalog]:

Research Areas >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Greco AV, et al. The metabolic effect of dodecanedioic acid infusion in non-insulin-dependent diabetic patients. Nutrition. 1998 Apr;14(4):351-7.  

Chemical & Physical Properties

[ Molecular Formula ]:
C12H18D4O4

[ Molecular Weight ]:
234.32500

[ Exact Mass ]:
234.17700

[ PSA ]:
74.60000

[ LogP ]:
3.05660

Related Compounds