2,3,5,6-TETRACHLOROPHENOL

Names

[ CAS No. ]:
935-95-5

[ Name ]:
2,3,5,6-TETRACHLOROPHENOL

[Synonym ]:
2,3,5,6-Tetrachlorophenol
EINECS 213-310-8
MFCD00044671

Chemical & Physical Properties

[ Density]:
1.709g/cm3

[ Boiling Point ]:
261ºC at 760mmHg

[ Melting Point ]:
114-116ºC

[ Molecular Formula ]:
C₆H₂Cl₄O

[ Molecular Weight ]:
231.89100

[ Flash Point ]:
11 °C

[ Exact Mass ]:
229.88600

[ PSA ]:
20.23000

[ LogP ]:
4.00580

[ Index of Refraction ]:
1.62

[ Storage condition ]:
APPROX 4°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SM9450000

CHEMICAL NAME :: Phenol, 2,3,5,6-tetrachloro-

CAS REGISTRY NUMBER :: 935-95-5

BEILSTEIN REFERENCE NO. :: 2049586

LAST UPDATED :: 199612

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C6-H2-Cl4-O

MOLECULAR WEIGHT :: 231.88

WISWESSER LINE NOTATION :: QR BG CG EG FG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - muscle weakness

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 109 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 48 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - gerbil

DOSE/DURATION :: 979 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 60 mg/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 241,175,1990

Safety Information

[ Symbol ]:

GHS02, GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H301 + H311 + H331-H370

[ Precautionary Statements ]:
P210-P260-P280-P301 + P310 + P330-P308 + P311-P403 + P233

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T,F

[ Risk Phrases ]:
25-37/38-41-39/23/24/25-23/24/25-11

[ Safety Phrases ]:
S26-S39-S45-S36/37-S16

[ RIDADR ]:
UN 2020 6.1/PG 3

[ RTECS ]:
SM9450000

[ HS Code ]:
2908199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2908199090

[ Summary ]:
HS: 2908199090. derivatives of polyphenols or phenol-alcohols containing only halogen substituents and their salts. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tariff:5.5%. general tariff:30.0%

Articles

Degradation of 2,4,5-trichlorophenol and 2,3,5,6-tetrachlorophenol by combining pulse electric discharge with bioremediation.

Appl. Microbiol. Biotechnol. 52(2) , 261-6, (1999)

Degradation of 2,4,5-trichlorophenol (2,4,5-TCP) and 2,3,5,6-tetrachlorophenol (TeCP) was studied using a two-stage approach that utilized efficient pulse electric discharge (PED) followed by biologic...

Acute dermal toxicity of tetrachlorophenols in the rat.

Bull. Environ. Contam. Toxicol. 31(6) , 680-5, (1983)