Published date: 2024-07-17 15:06:36
CAS number: 2160546-07-4
Name: 4-Piperidinamine, 1-[3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazin-6-yl]-4-methyl-
Price:
$700.0/100mg
$1200.0/250mg
$2400.0/1g
Purity: 98.0%
Stocking period: Inquiry
Stock: 3
Product Webpage: https://www.dcchemicals.com/product_show-IACS-13909.html
Detail Product Information:
IACS-13909 is a specific and potent allosteric inhibitor of SHP2 that suppresses the signaling of RTK/MAPK pathway and overcomes multiple mechanisms underlying osimertinib resistance. IACS-13909 potently impedes the proliferation of tumors with a broad spectrum of RTKs as the oncogenic driver. Importantly, in NSCLC models with acquired resistance to osimertinib, IACS-13909 administered as a single agent or in combination with osimertinib potently reduces tumor cell proliferation in vitro and in vivo. Together, our findings provide preclinical evidence for using a SHP2 inhibitor as a therapeutic strategy in acquired EGFR inhibitor-resistant NSCLC.
Name: DC Chemicals Limited Recommended
Chemsrc Level: Verified
Product #: 34949
Tel: 58447131
Address: Jinyu Rd100, pudong
Area: China(Mainland)
Contact: Tony Cao
Contact Phone #: 13564518121
Email: sales@dcchemicals.com
Website: http://www.dcchemicals.com
Detail
introduction:
D&C Chemicals provides a wide range of research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and Natural compounds for laboratory and scientific use.
D&C Chem has established a global network of thousands of customers from many research centers and Reagent companies in the USA, Europe and Japan.
We are the the official vendor of more than 500 universities and institutes including: Harvard University,Yale University,NIH/NCI, City of Hope ORG, PARTNERS ORG,John Hopkins University,Universit tsklinikum,Oxford University,Newcastle University,UNC,UCSF and many other universities and institutes. Our bioactive compounds received good feedback from our customers.
Our credo is committed to the adoption of different products, reliable quality, competitive prices and quality service to create value for customers.
Name: Shanghai Nianxing Industrial Co., Ltd
Area: China
Price:
$700.0/100mg
$1200.0/250mg
$2400.0/1g
Contact: Huang
Product Detail: IACS-13909
Name: ShangHai DC Chemicals Co.,Ltd
Area: China
Price:
$700.0/100mg
$1200.0/250mg
$2400.0/1g
Contact: Tony Lai
Product Detail: IACS-13909
Name: DC Chemicals Limited
Area: China
Price:
$700.0/100mg
$1200.0/250mg
$2400.0/1g
Contact: Tony Cao
Product Detail: IACS-13909
Get all suppliers by the below link:
4-Piperidinamine, 1-[3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazin-6-yl]-4-methyl- suppliers
2024-07-15 IACS-13909
2022-11-29 IACS-13909
2022-05-12 4-Piperidinamine, 1-[3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazin-6-yl]-4-methyl-
2023-10-31 IACS13909
2021-05-10 4-Piperidinamine, 1-[3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazin-6-yl]-4-methyl-
2024-04-03 IACS-13909
2022-09-23 IACS-13909
Get all price from the following link:
4-Piperidinamine, 1-[3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazin-6-yl]-4-methyl- price