Published date: 2024-07-17 15:06:43
CAS number: 832-68-8
Name: 6-Aminophenanthridine
Price:
$Inquiry/100mg
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Purity: 98.0%
Stocking period: 3 Day
Stock: 3
Product Webpage: https://www.dcchemicals.com/product_show-6-Aminophenanthridine.html
Detail Product Information:
6-Aminophenanthridine is an antiprion agent. It inhibits prion formation in yeast- and mammalian-based screening assays when used alone and, to a greater extent, when used in combination with the α2-adrenergic receptor agonist guanabenz. 6-Aminophenanthridine inhibits protein folding activity of the ribosome (PFAR) by directly competing with protein substrates for the active site and decreases the yield of refolded protein without affecting the refolding rate. It prevents progressive wing position defects in a Drosophila model of oculopharyngeal muscular dystrophy (OPMD) when larvae are raised on medium containing doses ranging from 300 to 400 μM and in adults following dietary administration of 1-3 mM doses. 6-Aminophenanthridine also reduces muscle degeneration and decreases the number of nuclear inclusions in thoracic muscle in a Drosophila model of OPMD.
Name: DC Chemicals Limited Recommended
Chemsrc Level: Verified
Product #: 34949
Tel: 58447131
Address: Jinyu Rd100, pudong
Area: China(Mainland)
Contact: Tony Cao
Contact Phone #: 13564518121
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Website: http://www.dcchemicals.com
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Name: Shanghai Nianxing Industrial Co., Ltd
Area: China
Price:
$Inquiry/100mg
$Inquiry/250mg
$Inquiry/500mg
Contact: Huang
Product Detail: 6-Aminophenanthridine
Name: DC Chemicals Limited
Area: China
Price:
$Inquiry/100mg
$Inquiry/250mg
$Inquiry/500mg
Contact: Tony Cao
Product Detail: 6-Aminophenanthridine
Name: Dayang Chem (Hangzhou) Co., Ltd.
Area: China
Price:
$Inquiry/100mg
$Inquiry/250mg
$Inquiry/500mg
Contact: Ms Wang
Product Detail: phenanthridin-6-amine
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