Published date: 2024-07-17 15:06:29
CAS number: 1301761-96-5
Name: GSK-114
Price:
$650.0/100mg
$1100.0/250mg
$2000.0/1g
Purity: 98.0%
Stocking period: 3 Day
Stock: 3
Product Webpage: https://www.dcchemicals.com/product_show-GSK-114.html
Detail Product Information:
GSK-114 is a potent and selective selective TNNI3K inhibitor (TNNI3 IC50 = 25nM; B-RafV600E IC50 = 1000 nM). GSK-114 displays significant bias (40-fold) for TNNI3K over B-Raf, exceptional broad spectrum kinase selectivity, and adequate oral exposure to enable its use in cellular and in vivo studies. Cardiac troponin I-interacting kinase (TNNI3K or CARK) is a member of the tyrosine-like kinase family that is selectively expressed in heart tissue. TNNI3K has been linked to the progression of dilated cardiomyopathy, cardiac hypertrophy, and ischemia/reperfusion injury using models that employ Tnni3k overexpressing or Tnni3k knockout animals.
Name: DC Chemicals Limited Recommended
Chemsrc Level: Verified
Product #: 34952
Tel: 58447131
Address: Jinyu Rd100, pudong
Area: China(Mainland)
Contact: Tony Cao
Contact Phone #: 13564518121
Email: sales@dcchemicals.com
Website: http://www.dcchemicals.com
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Name: Shanghai Nianxing Industrial Co., Ltd
Area: China
Price:
$650.0/100mg
$1100.0/250mg
$2000.0/1g
Contact: Yang
Product Detail: GSK114
Name: DC Chemicals Limited
Area: China
Price:
$650.0/100mg
$1100.0/250mg
$2000.0/1g
Contact: Tony Cao
Product Detail: GSK-114
Name: ShangHai DC Chemicals Co.,Ltd
Area: China
Price:
$650.0/100mg
$1100.0/250mg
$2000.0/1g
Contact: Tony Lai
Product Detail: GSK-114
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