Published date: 2024-07-17 15:06:37
CAS number: 2355377-13-6
Name: DDO-5936
Price:
$900.0/100mg
￥1700.0/250mg
￥3500.0/1g
Purity: 98.0%
Stocking period: 1 Day
Stock: 3
Product Webpage: https://www.dcchemicals.com/product_show-DDO-5936.html
Detail Product Information:
DDO-5936 is a potent PPI inhibitor targeting Hsp90-Cdc37 protein-protein interaction (PPI) as Orally Active Inhibitors for the Treatment of Colorectal Cancer. DDO-5936 disrupted the Hsp90-Cdc37 PPI both in vitro and in vivo via binding to a previously unknown site on Hsp90 involving Glu47, one of the binding determinants for the Hsp90-Cdc37 PPI, leading to selective down-regulation of Hsp90 kinase clients in HCT116 cells. In addition, inhibition of Hsp90-Cdc37 complex formation by DDO-5936 resulted in a remarkable cyclin-dependent kinase 4 decrease and consequent inhibition of cell proliferation through Cdc37-dependent cell cycle arrest.
Name: DC Chemicals Limited Recommended
Chemsrc Level: Verified
Product #: 34949
Tel: 58447131
Address: Jinyu Rd100, pudong
Area: China(Mainland)
Contact: Tony Cao
Contact Phone #: 13564518121
Email: sales@dcchemicals.com
Website: http://www.dcchemicals.com
Detail
introduction:
D&C Chemicals provides a wide range of research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and Natural compounds for laboratory and scientific use.
D&C Chem has established a global network of thousands of customers from many research centers and Reagent companies in the USA, Europe and Japan.
We are the the official vendor of more than 500 universities and institutes including: Harvard University,Yale University,NIH/NCI, City of Hope ORG, PARTNERS ORG,John Hopkins University,Universit tsklinikum,Oxford University,Newcastle University,UNC,UCSF and many other universities and institutes. Our bioactive compounds received good feedback from our customers.
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Name: Shanghai Nianxing Industrial Co., Ltd
Area: China
Price:
$900.0/100mg
￥1700.0/250mg
￥3500.0/1g
Contact: Huang
Product Detail: DDO-5936
Name: DC Chemicals Limited
Area: China
Price:
$900.0/100mg
￥1700.0/250mg
￥3500.0/1g
Contact: Tony Cao
Product Detail: DDO-5936
Name: ShangHai DC Chemicals Co.,Ltd
Area: China
Price:
$900.0/100mg
￥1700.0/250mg
￥3500.0/1g
Contact: Tony Lai
Product Detail: DDO-5936
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