Published date: 2024-01-10 21:46:08
CAS number: 2369979-67-7
Name: JHU 37152
Price:
￥Inquiry/1g
Purity: 98.9%
Stocking period: 1 Day
Stock: In Stock
Product Webpage: https://www.dcchemicals.com/product_show-jhu37152.html
Detail Product Information:
JHU37152 is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.8 nM and 8.7 nM for human muscarinic acetylcholine M3 receptors (hM3Dq) and hM4Di in vitro, respectively. And EC50 values are 5 nM and 0.5 nM for hM3Dq and hM4Di in fluorescent and BRET-based assays in HEK-293 cells, respectively.,hM4Di [1](Cell-free assay)
hM3Dq [1](Cell-free assay)
hM3Dq [1](Cell-free assay)
hM4Di [1](Cell-free assay)
0.5 nM(EC50)
1.8 nM(Ki)
5 nM(EC50)
8.7 nM(Ki),JHU37152 is a potent DREADD agonist with high potency and efficacy in fluorescent and BRET-based assays in HEK-293 cells, whereas no responses are observed in untransfected HEK-293 cells.[1],JHU37152 exhibits high in vivo DREADD potency. JHU37152 exhibits selective [3H]clozapine displacement from DREADDs in brain tissue from WT and D1-DREADD mice.[1]
Name: DC Chemicals Limited Recommended
Chemsrc Level: Verified
Product #: 34949
Tel: 58447131
Address: Jinyu Rd100, pudong
Area: China(Mainland)
Contact: Tony Cao
Contact Phone #: 13564518121
Email: sales@dcchemicals.com
Website: http://www.dcchemicals.com
Detail
introduction:
D&C Chemicals provides a wide range of research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and Natural compounds for laboratory and scientific use.
D&C Chem has established a global network of thousands of customers from many research centers and Reagent companies in the USA, Europe and Japan.
We are the the official vendor of more than 500 universities and institutes including: Harvard University,Yale University,NIH/NCI, City of Hope ORG, PARTNERS ORG,John Hopkins University,Universit tsklinikum,Oxford University,Newcastle University,UNC,UCSF and many other universities and institutes. Our bioactive compounds received good feedback from our customers.
Our credo is committed to the adoption of different products, reliable quality, competitive prices and quality service to create value for customers.
Name: Shanghai Nianxing Industrial Co., Ltd
Area: China
Price:
￥Inquiry/1g
Contact: Huang
Product Detail: JHU37152
Name: DC Chemicals Limited
Area: China
Price:
￥Inquiry/1g
Contact: Tony Cao
Product Detail: JHU37152
Name: ShangHai DC Chemicals Co.,Ltd
Area: China
Price:
￥Inquiry/1g
Contact: Tony Lai
Product Detail: JHU37152
Get all suppliers by the below link:
2024-07-15 JHU37152
2022-11-29 JHU37152
2022-05-12 5H-Dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-ethyl-1-piperazinyl)-1-fluoro-
Get all price from the following link: