Published date: 2024-07-17 15:06:33
CAS number: 1203036-62-7
Name: Kv2.1-syntaxin inhibitor 15
Price:
$Inquiry/100mg
$Inquiry/250mg
$Inquiry/1g
Purity: 98.0%
Stocking period: 3 Day
Stock: 3
Product Webpage: https://www.dcchemicals.com/product_show-kv2.1-syntaxininhibitor15.html
Detail Product Information:
Kv2.1-syntaxin inhibitor 15 (Kv2.1-syntaxin-IN-15, Cpd5) is a small molecule Kv2.1-syntaxin-binding inhibitor (IC50=5.5 uM) with neuroprotective properties.Kv2.1-syntaxin inhibitor 15 competitively binds syntaxin against C1aB-containing Kv2.1 peptides with IC50 of 5.5 uM.Kv2.1-syntaxin inhibitor 15 (10 uM) significantly diminished threo-β-benzyloxyaspartate (TBOA, 75 uM)-induced toxicity neuronal cultures, ameliorated significant cellular damage, by preventing the expression of enhanced Kv2.1-mediated K+ currents.Kv2.1-syntaxin inhibitor 15 is a first-in-class inhibitor of Kv2.1 binding to Syntaxin, likely due to inhibition of the C1a region of Kv2.1 binding to syntaxin.Cpd5 (10 μM) does not affect evoked AMPAR EPSCs in layer 2/3 corticocallosal neurons in the mouse auditory cortex.
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Name: Shanghai Nianxing Industrial Co., Ltd
Area: China
Price:
$Inquiry/100mg
$Inquiry/250mg
$Inquiry/1g
Contact: Yang
Product Detail: Kv2.1-syntaxin inhibitor 15
Name: DC Chemicals Limited
Area: China
Price:
$Inquiry/100mg
$Inquiry/250mg
$Inquiry/1g
Contact: Tony Cao
Product Detail: Kv2.1-syntaxin inhibitor 15
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2024-07-17 Kv2.1-syntaxin inhibitor 15
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