Published date: 2024-07-17 15:06:30
CAS number: 2660250-10-0
Name: BLU-945
Price:
$600.0/100mg
$1100.0/250mg
$2200.0/1g
Purity: 98.0%
Stocking period: 3 Day
Stock: 3
Product Webpage: https://www.dcchemicals.com/product_show-blu-945.html
Detail Product Information:
BLU-945 is a potent, mutant-selective inhibitor of EGFR T790M/C797S and EGFR+/T790M mutations (IC50 1000-fold selectivity over EGFR WT.BLU-945 achieves potent EGFR pathway inhibition in NCI-H1975 EGFRL858R/T790M, Ba/F3 EGFRL858R/T790M/C797S, and Ba/F3 EGFRex19del/T790M/C797S cell lines and a large window relative to EGFRWT inhibition.Oral administration of BLU-945 to tumor-bearing mice demonstrated potent EGFR pathway inhibition and anti-tumor activity at well-tolerated doses in the subcutaneous NCI-H1975 CDX model, and osimertinib-resistant CDX and PDX models.
Name: DC Chemicals Limited Recommended
Chemsrc Level: Verified
Product #: 34951
Tel: 58447131
Address: Jinyu Rd100, pudong
Area: China(Mainland)
Contact: Tony Cao
Contact Phone #: 13564518121
Email: sales@dcchemicals.com
Website: http://www.dcchemicals.com
Detail
introduction:
D&C Chemicals provides a wide range of research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and Natural compounds for laboratory and scientific use.
D&C Chem has established a global network of thousands of customers from many research centers and Reagent companies in the USA, Europe and Japan.
We are the the official vendor of more than 500 universities and institutes including: Harvard University,Yale University,NIH/NCI, City of Hope ORG, PARTNERS ORG,John Hopkins University,Universit tsklinikum,Oxford University,Newcastle University,UNC,UCSF and many other universities and institutes. Our bioactive compounds received good feedback from our customers.
Our credo is committed to the adoption of different products, reliable quality, competitive prices and quality service to create value for customers.
Name: Shanghai Nianxing Industrial Co., Ltd
Area: China
Price:
$600.0/100mg
$1100.0/250mg
$2200.0/1g
Contact: Yang
Product Detail: BLU-945
Name: ShangHai DC Chemicals Co.,Ltd
Area: China
Price:
$600.0/100mg
$1100.0/250mg
$2200.0/1g
Contact: Tony Lai
Product Detail: BLU-945
Name: DC Chemicals Limited
Area: China
Price:
$600.0/100mg
$1100.0/250mg
$2200.0/1g
Contact: Tony Cao
Product Detail: BLU-945
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