p-tolylmethanol

Names

[ CAS No. ]:
589-18-4

[ Name ]:
p-tolylmethanol

[Synonym ]:
p-methyl-benzyl alcohol
4-methyl-benzyl alcohol
P-TOLYLCARBINOL
4-Me-benzyl alcohol
RARECHEM AL BD 0113
p-Tolyl-methanol
Q1R D1
PMAL
4-Methylbenzyl alcohol
(4-methylphenyl)methyl alcohol
p-methylbenzyl
Benzenemethanol, 4-methyl-
EINECS 209-639-1
METHYLBENZYL ALCOHOL
p-Toluyl alcohol
(4-Methylphenyl)methanol
p-Tolymethanol
MFCD00004664
p-tolylmethanol
4-TOLYL CARBINOL

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
218.4±8.0 °C at 760 mmHg

[ Melting Point ]:
59-61 °C(lit.)

[ Molecular Formula ]:
C₈H₁₀O

[ Molecular Weight ]:
122.164

[ Flash Point ]:
105.0±3.5 °C

[ Exact Mass ]:
122.073166

[ PSA ]:
20.23000

[ LogP ]:
1.50

[ Vapour Pressure ]:
0.1±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.540

[ Storage condition ]:
Store at R.T.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DO9370000

CHEMICAL NAME :: Benzyl alcohol, p-methyl-

CAS REGISTRY NUMBER :: 589-18-4

BEILSTEIN REFERENCE NO. :: 1856550

LAST UPDATED :: 199701

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C8-H10-O

MOLECULAR WEIGHT :: 122.18

WISWESSER LINE NOTATION :: Q1R D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,839,1982 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3900 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,839,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 12,347,1962

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 324 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 104,793,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,839,1982

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
DO9370000

[ HS Code ]:
2902909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2902909090

[ Summary ]:
2902909090 other aromatic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

Articles

Green procedure for the preparation of scented alcohols from carbonyl compounds.

Int. J. Cosmet. Sci. 30(2) , 139-44, (2008)

Several alcohols--interesting as cosmetic fragrances whose main preparative route on an industrial scale or in the research laboratory is the reduction of the corresponding carbonyl compound--were obt...

Polycarbonates derived from glucose via an organocatalytic approach.

J. Am. Chem. Soc. 135(18) , 6826-9, (2013)

An organocatalyzed ring-opening polymerization methodology was developed for the preparation of polycarbonates derived from glucose as a natural product starting material. The cyclic 4,6-carbonate mon...

Assembly of Mesoporous Metal-Organic Framework Templated by an Ionic Liquid/Ethylene Glycol Interface.

ChemPhysChem 16 , 2317-21, (2015)

We propose a facile room-temperature synthesis of a metal-organic framework (MOF) with a bimodal mesoporous structure (3.9 and 17-28 nm) in an ionic liquid (IL)/ethylene glycol (EG) mixture. The X-ray...