DeMethoxycapillarisin

Names

[ Name ]:
DeMethoxycapillarisin

[Synonym ]:
4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenoxy)-
5,7-Dihydroxy-2-(4-hydroxyphenoxy)-4H-chromen-4-one
Demethoxycapillarisin
6-Demethoxycapillarisin
6-demethoxycapilarisin

Biological Activity

[Description]:

Demethoxycapillarisin (6-Demethoxycapillarisin) inhibits PEPCK mRNA levels (IC50: 43 μM) by activation of the PI3K pathway. Demethoxycapillarisin decreases glucose production[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. Govorko D, et al. Polyphenolic compounds from Artemisia dracunculus L. inhibit PEPCK gene expression and gluconeogenesis in an H4IIE hepatoma cell line. Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1503-10.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
535.9±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₅H₁₀O₆

[ Molecular Weight ]:
286.236

[ Flash Point ]:
207.5±23.6 °C

[ Exact Mass ]:
286.047729

[ PSA ]:
100.13000

[ LogP ]:
2.70

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.729

Safety Information

[ Hazard Codes ]:
Xi

DeMethoxycapillarisin

Names

Biological Activity

Chemical & Physical Properties

Safety Information

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds