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DiSC3(5)

Names

[ CAS No. ]:
53213-94-8

[ Name ]:
DiSC3(5)

[Synonym ]:
MFCD00075033
3-Propyl-2-[5-[3-propyl-2(3H)-benzothiazolylidene]-1,3-pentadienyl]benzothiazolium Iodide
3,3'-Dipropylthiadicarbocyanine iodide
3,3'-Dipropylthiadicarbocyanine iodide,DiSC3(5)
5-(3-Propylbenzothiazol-2-ylidene)-1-(3-propylbenzothiazolium-2-yl)-1,3-pentadiene Iodide

Biological Activity

[Description]:

DiSC3(5) is a fluorescent probe often used as a tracer dye to assess the mitochondrial membrane potential[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Yamamoto T, et al. Multiple effects of DiS-C3(5) on mitochondrial structure and function. Eur J Biochem. 2004;271(17):3573-3579.

Chemical & Physical Properties

[ Melting Point ]:
245ºC (dec.)(lit.)

[ Molecular Formula ]:
C25H27IN2S2

[ Molecular Weight ]:
546.53000

[ Exact Mass ]:
546.06600

[ PSA ]:
65.29000

[ LogP ]:
3.36020

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

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J. Med. Food 18 , 516-23, (2015)

The excessive release of glutamate is a critical element in the neuropathology of acute and chronic brain disorders. The purpose of the present study was to investigate the effect and possible mechani...


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Related Compounds