SB297006
Names
Biological Activity
[Description]:
[Related Catalog]:
[Target]
CCR3[1]
[In Vitro]
[Cell Assay]
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Melting Point ]:
121 °C
[ Molecular Formula ]:
C18H18N2O5
[ Molecular Weight ]:
342.34600
[ Exact Mass ]:
342.12200
[ PSA ]:
101.22000
[ LogP ]:
3.41310
Safety Information
[ Symbol ]:
GHS07, GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H400
[ Precautionary Statements ]:
P273
[ RIDADR ]:
UN 3077 9 / PGIII
Precursor & DownStream
Precursor
DownStream
Articles
Expert Opin. Ther. Pat. 19(8) , 1109-32, (2009)
Since the mid-1990s, there has been significant effort invested in the discovery and clinical development of CC chemokine receptor-3 (CCR3) antagonists as potential therapeutics for airway disease.A p...
Cytokine modulators as novel therapies for asthma.Annu. Rev. Pharmacol. Toxicol. 42 , 81-98, (2002)
Cytokines play a critical role in orchestrating and perpetuating inflammation in asthmatic airways and several specific cytokine and chemokine inhibitors are now in development for the treatment of as...