Tribenoside Price from Supplier Brand Ningbo Excellent New Materials Co Ltd on Chemsrc.com

Published date: 2024-07-11 15:20:34

CAS number: 10310-32-4

Price:
￥300.0/1kg

Purity: 99.5%

Stocking period: 7 Day

Stock: Inquiry

Detail Product Information:
Tribenoside is a vasoprotective agent, can be used for the research of hemorrhoids. Tribenoside has mild anti-inflammatory, analgesic, and wound healing properties[1].
Related Catalog
Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology
In Vitro Tribenoside (1 nM-100 µM) exhibits cytotoxic effect against HeLa cells with the EC50 of 13.74 µM[2]. Cell Viability Assay[2] Cell Line: HeLa cells Concentration: 1 nM, 10 nM, 100 nM, 1 µM, 10 µM, 100 µM Incubation Time: 72 hours Result: Reduced HeLa cells viability in a dose-responsive manner.
In Vivo Tribenoside (oral administration in doses of 500 and 1,200 mg/kg weekly) significantly decreases in the development of osteoporosis[3]. Animal Model: male C57 black mice[3] Dosage: 500 and 1,200 mg/kg weekly Administration: Oral administration Result: Led to a significant reduction in the overall arthrotic involvement.
References
[1]. Yamato Kikkawa, et al. The influence of Tribenoside on expression and deposition of epidermal laminins in HaCaT cells. Biol Pharm Bull. 2010;33(2):307-10.

[2]. Yu-Chen Lo, et al. Computational Cell Cycle Profiling of Cancer Cells for Prioritizing FDA-Approved Drugs with Repurposing Potential. Sci Rep. 2017 Sep 12;7(1):11261.

[3]. G Wilhelmi, et al. Suitability of the C57 black mouse as an experimental animal for the study of skeletal changes due to ageing, with special reference to osteo-arthrosis and its response to tribenoside. Pharmacology. 1976;14(4):289-96.

Chemical & Physical Properties
Density 1.19g/cm3
Boiling Point 618.9ºC at 760mmHg
Molecular Formula C29H34O6
Molecular Weight 478.57700
Flash Point 328.1ºC
Exact Mass 478.23600
PSA 66.38000
LogP 4.49630
Vapour Pressure 3.55E-16mmHg at 25°C
Index of Refraction 1.59
Storage condition -20°C
Toxicological Information
CHEMICAL IDENTIFICATION
RTECS NUMBER :
LZ4993000
CHEMICAL NAME :
Glucofuranoside, ethyl-3,5,6-tri-o-benzyl-, D-
CAS REGISTRY NUMBER :
10310-32-4
LAST UPDATED :
199603
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C29-H34-O6
MOLECULAR WEIGHT :
478.63
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>20 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 8,2748,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 8,2748,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>20 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 8,2748,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>30 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 8,2748,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 8,2748,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>30 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 8,2748,1974 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
84 gm/kg/2W-I
TOXIC EFFECTS :
Liver - changes in liver weight
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 8,2789,1974
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
65 gm/kg/30D-I
TOXIC EFFECTS :
Liver - fatty liver degeneration Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 8,2748,1974
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
156 gm/kg/26W-I
TOXIC EFFECTS :
Liver - fatty liver degeneration Liver - changes in liver weight Endocrine - changes in adrenal weight
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 8,2772,1974
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
84 gm/kg/2W-I
TOXIC EFFECTS :
Liver - changes in liver weight Endocrine - changes in spleen weight Endocrine - changes in thymus weight
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 8,2789,1974
Safety Information
RIDADR NONH for all modes of transport

Name: Ningbo Excellent New Materials Co Ltd

Chemsrc Level: Unverified

Product #: 16

Tel: +86-13626849982

Address: Chaoyang Rd 667, Shanghe, Jiangshan Yinzhou Ningbo Zhejiang, China 315191

Area: China(Mainland)

Contact: Mr Xu

Contact Phone #: 13626849982

Email: three_xu@163.com

Website: http://www.excellentvial.com/

Major Market: West

Annual Trade Volume: USD3000000

Foreign Trade % of Salers: 60%

Major partners: confidential

Detail introduction:
Ningbo Excellent New Materials Co Ltd，brand as "HAMAG", was founded in 2005. Started from high quality products, Hamag is now a production-oriented enterprise integrating R&D, design, production and sales. With a factory area of more than 7,000 square meters, nearly 90 employees, a 100,000-level dust-free purification production workshop and international advanced automation equipment, Hamag can meet the development and production requirements of products in this field in terms of high purity and high cleanliness. ISO 9001 certificated.

Name: Shanghai Nianxing Industrial Co., Ltd

Area: China

Price:
￥300.0/1kg

Contact: Huang

Product Detail: Tribenoside

Name: ShangHai DC Chemicals Co.,Ltd

Area: China

Price:
￥300.0/1kg

Contact: Tony Lai

Product Detail: Ba 2140

Name: DC Chemicals Limited

Area: China