18β-Glycyrrhetyl-3-O-sulfate
Names
[ CAS No. ]:
10251-38-4
[ Name ]:
18β-Glycyrrhetyl-3-O-sulfate
Biological Activity
[Description]:
18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)) is a potent type 2 11β-hydroxysteroid dehydrogenase (11β-HSD2) inhibitor with an IC50 of 0.10 µM using rat kidney microsome. 18β-Glycyrrhetyl-3-O-sulfate is the major metabolite of Glycyrrhetinic acid (GA). 18β-Glycyrrhetyl-3-O-sulfate is the substrate of organic anion transporter (OAT) 1 and OAT3. 18β-Glycyrrhetyl-3-O-sulfate has anti-inflammatory effects and has the potential for pseudohyperaldosteronism research[1][2].
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C30H46O7S
[ Molecular Weight ]:
550.75