(-)-n-methylphysostigmine

Names

[ CAS No. ]:
103877-07-2

[ Name ]:
(-)-n-methylphysostigmine

[Synonym ]:
Physostigmine analog 33

Chemical & Physical Properties

[ Density]:
1.152g/cm3

[ Boiling Point ]:
406.7ºC at 760 mmHg

[ Molecular Formula ]:
C16H23N3O2

[ Molecular Weight ]:
289.37300

[ Flash Point ]:
199.8ºC

[ Exact Mass ]:
289.17900

[ PSA ]:
36.02000

[ LogP ]:
2.11900

[ Appearance of Characters ]:
solid | white

[ Vapour Pressure ]:
7.97E-07mmHg at 25°C

[ Index of Refraction ]:
1.566

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
H2O: 1.9 mg/mL

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
UN 1544 6.1/PG 2

[ WGK Germany ]:
3

Articles

Anti-proliferative effect and induction of apoptosis in androgen-independent human prostate cancer cells by 1,5-bis(2-hydroxyphenyl)-1,4-pentadiene-3-one.

Molecules 20(2) , 3406-30, (2015)

Curcumin has poor in vivo absorption and bioavailability, highlighting a need for new curcumin analogues with better characteristics in these aspects. The aim of this study is to determine the anti-ca...

Levosimendan inhibits peroxidation in hepatocytes by modulating apoptosis/autophagy interplay.

PLoS ONE 10(4) , e0124742, (2015)

Levosimendan protects rat liver against peroxidative injuries through mechanisms related to nitric oxide (NO) production and mitochondrial ATP-dependent K (mitoKATP) channels opening. However, whether...

Inhibition of acetylcholinesterase from electric eel by (-)-and (+)-physostigmine and related compounds.

FEBS Lett. 201 , 190-192, (1986)

Unnatural (+)-physostigmine (2) inhibited acetylcholinesterase (AChE) from electric eel considerably less than natural (-)-physostigmine (1), but 2 may because of its possible lower toxicity still be ...


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Related Compounds