β-D-Glucopyranosiduronic acid, (R)-cyanophenylmethyl
Names
[ CAS No. ]:
1332-94-1
[ Name ]:
β-D-Glucopyranosiduronic acid, (R)-cyanophenylmethyl
Chemical & Physical Properties
[ Density]:
1.55g/cm3
[ Boiling Point ]:
581.1ºC at 760mmHg
[ Molecular Formula ]:
C14H15NO7
[ Molecular Weight ]:
309.27100
[ Flash Point ]:
305.2ºC
[ Exact Mass ]:
309.08500
[ PSA ]:
140.24000
[ Vapour Pressure ]:
2.41E-14mmHg at 25°C
[ Index of Refraction ]:
1.634
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- OD9910000
- CHEMICAL NAME :
- Laetrile
- CAS REGISTRY NUMBER :
- 1332-94-1
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C14-H15-N-O7
- MOLECULAR WEIGHT :
- 309.30
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 60 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Gastrointestinal - hypermotility, diarrhea Liver - fatty liver degeneration
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 198 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - hallucinations, distorted perceptions Lungs, Thorax, or Respiration - dyspnea
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - man
- DOSE/DURATION :
- 1286 mg/kg/24W
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Sense Organs and Special Senses (Eye) - ptosis Behavioral - muscle weakness
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Multiple routes
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 4170 mg/kg/8W
- TOXIC EFFECTS :
- Gastrointestinal - nausea or vomiting Skin and Appendages - dermatitis, other (after systemic exposure) Nutritional and Gross Metabolic - body temperature increase
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - respiratory stimulation
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 9600 pmol/plate
- REFERENCE :
- SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 198,625,1977
Safety Information
[ HS Code ]:
3004500000
Customs
[ HS Code ]: 3004500000