n-allylnormetazocine

Names

[ CAS No. ]:
14198-28-8

[ Name ]:
n-allylnormetazocine

[Synonym ]:
l-N-Allylnormetazocine
(-)-ANMC
2,6-Methano-3-benzazocin-8-ol,1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(2-propenyl)-,(2R,6R,11R)
(-)-SKF 10.047
2,6-Methano-3-benzazocin-8-ol,1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(2-propenyl)-,(2R-(2alpha,6alpha,11R*))

Chemical & Physical Properties

[ Density]:
1.055g/cm3

[ Boiling Point ]:
373.6ºC at 760mmHg

[ Molecular Formula ]:
C17H23NO

[ Molecular Weight ]:
257.37100

[ Flash Point ]:
169.9ºC

[ Exact Mass ]:
257.17800

[ PSA ]:
23.47000

[ LogP ]:
3.04030

[ Appearance of Characters ]:
solid | white

[ Vapour Pressure ]:
4.11E-06mmHg at 25°C

[ Index of Refraction ]:
1.559

[ Water Solubility ]:
H2O: soluble

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H332

[ Precautionary Statements ]:
P280

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Sigma-1 receptor stimulation attenuates calcium influx through activated L-type Voltage Gated Calcium Channels in purified retinal ganglion cells.

Exp. Eye Res. 107 , 21-31, (2013)

Sigma-1 receptors (σ-1rs) exert neuroprotective effects on retinal ganglion cells (RGCs) both in vivo and in vitro. This receptor has unique properties through its actions on several voltage-gated and...

The C-terminal amidated analogue of the substance P (SP) fragment SP(1-7) attenuates the expression of naloxone-precipitated withdrawal in morphine dependent rats.

Peptides 30 , 2418-2422, (2009)

We previously demonstrated that intracerebroventricular (i.c.v.) administration of the substance P (SP) aminoterminal fragment SP(1-7) attenuates the expression of morphine withdrawal in the male rat....

Antagonist action of progesterone at σ-receptors in the modulation of voltage-gated sodium channels.

Am. J. Physiol. Cell Physiol. 300(2) , C328-37, (2011)

σ-Receptors are integral membrane proteins that have been implicated in a number of biological functions, many of which involve the modulation of ion channels. A wide range of synthetic ligands activa...


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Related Compounds