Nabam
Names
[ CAS No. ]:
142-59-6
[ Name ]:
Nabam
[Synonym ]:
x-spor
Dithane D-14
Dinatriumethan-1,2-diylbis(dithiocarbamat)
Nabam
ethylenebis(dithiocarbamate) disodium salt
chem-bam
nabasan
MFCD00069382
ent9106
Carbamodithioic acid, N,N'-1,2-ethanediylbis-, sodium salt (1:2)
D-14(R)
disodium N,N’-1,2-ethanediylbis(carbamodithioate)
disodium N,N’-ethane-1,2-diyldicarbamodithioate
D-14
carbond
EINECS 205-547-0
Disodium 1,2-ethanediyldicarbamodithioate
disodium ethylenebis(dithiocarbamate)
N,N'-ethane-1,2-diyl-bis-dithiocarbamic acid,disodium salt
disodium ethylenebisdithiocarbamate
Disodium ethane-1,2-diyldicarbamodithioate
Chemical & Physical Properties
[ Density]:
1.342 g/mL at 25 °C(lit.)
[ Boiling Point ]:
308.2ºC at 760 mmHg
[ Melting Point ]:
78-81ºC
[ Molecular Formula ]:
C4H6N2Na2S4
[ Molecular Weight ]:
256.343
[ Flash Point ]:
140.2ºC
[ Exact Mass ]:
255.920914
[ PSA ]:
138.84000
[ LogP ]:
1.91220
[ Index of Refraction ]:
n20/D 1.532(lit.)
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- FA6825000
- CHEMICAL NAME :
- Carbamic acid, ethylenebis(dithio-, disodium salt
- CAS REGISTRY NUMBER :
- 142-59-6
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 14
- MOLECULAR FORMULA :
- C4-H6-N2-S4.2Na
- MOLECULAR WEIGHT :
- 256.34
- WISWESSER LINE NOTATION :
- SUYSHM2MYUS&SH &-NA- 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 395 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 580 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 235 mg/kg/28D-C
- TOXIC EFFECTS :
- Endocrine - other changes Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4725 mg/kg/7D-I
- TOXIC EFFECTS :
- Endocrine - changes in spleen weight
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 194 mg/kg
- SEX/DURATION :
- female 6-14 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - extra-embryonic structures (e.g., placenta, umbilical cord) Reproductive - Effects on Embryo or Fetus - fetal death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 418 mg/kg
- SEX/DURATION :
- female 6-14 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth)
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Microorganism - not otherwise specified
- DOSE/DURATION :
- 1000 ppm
- REFERENCE :
- MMAPAP Mycopathologia et Mycologia Applicata. (The Hague, Netherlands) V.5-54(4), 1950-74. For publisher information, see MYCPAH. Volume(issue)/page/year: 50,233,1973 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84470 No. of Facilities: 111 (estimated) No. of Industries: 4 No. of Occupations: 6 No. of Employees: 798 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84470 No. of Facilities: 500 (estimated) No. of Industries: 14 No. of Occupations: 11 No. of Employees: 7277 (estimated) No. of Female Employees: 33 (estimated)
Safety Information
[ Symbol ]:
GHS07, GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H317-H335-H410
[ Precautionary Statements ]:
P261-P273-P280-P501
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
Xn: Harmful;N: Dangerous for the environment;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
26-36/37/39-61-60-46-24/25-8
[ RIDADR ]:
UN3077 9/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
FA6825000
[ Packaging Group ]:
II
[ Hazard Class ]:
8
[ HS Code ]:
29163900
Customs
[ HS Code ]: 29163900
Articles
Toxicol. Eur. Res. 3(6) , 285-91, (1981)
Nabam (fungicide dithiocarbamate) has been incorporated with the diet of rats during six months (the doses were: 0, 10, 50, 100, 500, 1000 and 2000 ppm). It decreases significantly the hepatic microso...
Ultrastructural and histological study of degenerative changes in the antennal glands, hepatopancreas, and midgut of grass shrimp exposed to two dithiocarbamate biocides.J. Invertebr. Pathol. 41(3) , 281-300, (1983)
The histological and ultrastructural alterations observed in the antennal glands, hepatopancreas, and midgut of grass shrimp exposed to either a 50% potassium dimethyldithiocarbamate biocide (Busan-85...
Studies on the mechanism of nabam- and zineb-induced inhibition of the hepatic microsomal monooxygenases of the male rat.Toxicol. Appl. Pharmacol. 81(3 Pt 1) , 460-8, (1985)
In vitro effects of the ethylene bis-dithiocarbamate fungicides, nabam and zineb, on the hepatic microsomal monooxygenases of male rats were examined. Incubation of nabam and zineb with hepatic micros...