DL-Glutamic acid-d5

Names

[ Name ]:
DL-Glutamic acid-d5

[Synonym ]:
DL-Glutamic acid-2,3,3,4,4-d5
glutamic acid-d5
Glutamic-2,3,3,4,4-d acid
glutamic acid-2,3,3,4,4-d5
(2,3,3,4,4-H)Glutamic acid
2,3,3,4,4-pentadeuterio-glutamic acid

Biological Activity

[Description]:

DL-Glutamic acid-d5 is the deuterium labeled DL-Glutamic acid. DL-Glutamic acid is the conjugate acid of Glutamic acid, which acts as a fundamental metabolite. Comparing with the second phase of polymorphs α and β L-Glutamic acid, DL-Glutamic acid presents better stability[1].

[Related Catalog]:

Research Areas >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
333.8±32.0 °C at 760 mmHg

[ Melting Point ]:
185ºC (dec)(lit.)

[ Molecular Formula ]:
C₅H₄D₅NO₄

[ Molecular Weight ]:
152.160

[ Flash Point ]:
155.7±25.1 °C

[ Exact Mass ]:
152.084549

[ PSA ]:
100.62000

[ LogP ]:
-1.43

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.522

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport