Zaragozic acid A trisodium salt
Names
[ CAS No. ]:
144541-82-2
[ Name ]:
Zaragozic acid A trisodium salt
[Synonym ]:
Zaragozic acid A is also known as Squalestatin A, Squalestatin S1, and L 694599.
Chemical & Physical Properties
[ Molecular Formula ]:
C35H43Na3O14
[ Molecular Weight ]:
756.677
[ Exact Mass ]:
756.234619
[ Water Solubility ]:
Soluble in ethanol (10 mg/ml), and DMSO (10 mg/ml, heating may be required).
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
Articles
Mol. Neurobiol. 51 , 1116-29, (2015)
The cerebellum is an important locus for motor learning and higher cognitive functions, and Purkinje cells constitute a key component of its circuit. Biochemically, significant turnover of cholesterol...
OX40 complexes with phosphoinositide 3-kinase and protein kinase B (PKB) to augment TCR-dependent PKB signaling.J. Immunol. 186 , 3547-55, (2011)
T lymphocyte activation requires signal 1 from the TCR and signal 2 from costimulatory receptors. For long-lasting immunity, growth and survival signals imparted through the Akt/protein kinase B (PKB)...
Mechanisms for autophagy modulation by isoprenoid biosynthetic pathway inhibitors in multiple myeloma cells.Oncotarget 6 , 41535-49, (2015)
Multiple myeloma (MM) is characterized by the production of monoclonal protein (MP). We have shown previously that disruption of the isoprenoid biosynthetic pathway (IBP) causes a block in MP secretio...