α,β-METHYLENEGUANOSINE 5'-DIPHOSPHATE SODIUM SALT

Names

[ CAS No. ]:
161308-39-0

[ Name ]:
α,β-METHYLENEGUANOSINE 5'-DIPHOSPHATE SODIUM SALT

[Synonym ]:
A,B-methyleneguanosine 5'-diphosphate,*sodium
GPCP SODIUM SALT
GMPCP,SODIUM SALT

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₁H₁₅N₅Na₂O₁₀P₂

[ Molecular Weight ]:
485.19100

[ Exact Mass ]:
485.00900

[ PSA ]:
268.62000

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

Articles

Role of guanine nucleotides in the vinblastine-induced self-association of tubulin: effects of guanosine alpha,beta-methylenetriphosphate and guanosine alpha,beta-methylenediphosphate.

Biochemistry 36 , 12828-12835, (1997)

It is now well established that guanine nucleotides are allosteric effectors of the vinca alkaloid-induced self-association of tubulin. GDP enhances self-association for vinblastine-, vincristine- and...

Structural changes accompanying GTP hydrolysis in microtubules: information from a slowly hydrolyzable analogue guanylyl-(alpha,beta)-methylene-diphosphonate.

J. Cell Biol. 128 , 117-125, (1995)

We have used cryoelectron microscopy to try to understand the structural basis for the role of GTP hydrolysis in destabilizing the microtubule lattice. We have measured a structural difference introdu...

Helical tubes of FtsZ from Methanococcus jannaschii.

Biol. Chem. 381 , 993-999, (2000)

Bacterial cell division depends on the formation of a cytokinetic ring structure, the Z-ring. The bacterial tubulin homologue FtsZ is required for Z-ring formation. FtsZ assembles into various polymer...