2',3',5'-Tri-O-benzoyl-6-azauridine

Names

[ CAS No. ]:
1627-29-8

[ Name ]:
2',3',5'-Tri-O-benzoyl-6-azauridine

[Synonym ]:
1,2,4-Triazine-3,5(2H,4H)-dione, 2-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-
2-(2,3,5-Tri-O-benzoyl-β-D-ribofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione

Biological Activity

[Description]:

2',3',5'-Tri-O-benzoyl-6-azauridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C29H23N3O9

[ Molecular Weight ]:
557.51

[ Exact Mass ]:
557.143433

[ LogP ]:
1.80

[ Index of Refraction ]:
1.659

Related Compounds