5-[(4-methylpiperazin-1-yl)methyl]-7-phenyl-[1,2]oxazolo[4,5-d]pyrimidine-3-carboxamide
Names
[ CAS No. ]:
165611-03-0
[ Name ]:
5-[(4-methylpiperazin-1-yl)methyl]-7-phenyl-[1,2]oxazolo[4,5-d]pyrimidine-3-carboxamide
[Synonym ]:
3-Carbamido-5-(4'-methylpiperazinomethyl)-7-phenylisoxazolo(4,5-d)pyrimidine
5-((4-Methyl-1-piperazinyl)methyl)-7-phenylisoxazolo(4,5-d)pyrimidine-3-carboxamide
Isoxazolo(4,5-d)pyrimidine-3-carboxamide,5-((4-methyl-1-piperazinyl)methyl)-7-phenyl
Chemical & Physical Properties
[ Density]:
1.317g/cm3
[ Boiling Point ]:
544.4ºC at 760mmHg
[ Molecular Formula ]:
C18H20N6O2
[ Molecular Weight ]:
352.39000
[ Flash Point ]:
283.1ºC
[ Exact Mass ]:
352.16500
[ PSA ]:
102.37000
[ LogP ]:
1.89110
[ Vapour Pressure ]:
6.52E-12mmHg at 25°C
[ Index of Refraction ]:
1.648
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NY3401784
- CHEMICAL NAME :
- Isoxazolo(4,5-d)pyrimidine-3-carboxamide, 5-((4-methyl-1-piperazinyl)methyl)-7-phenyl-
- CAS REGISTRY NUMBER :
- 165611-03-0
- LAST UPDATED :
- 199606
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C18-H20-N6-O2
- MOLECULAR WEIGHT :
- 352.44
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella Postale 227, 27100 Pavia, Italy) V.44- 1989- Volume(issue)/page/year: 50,183,1995