DENV-IN-8

Names

[ CAS No. ]:
1809464-07-0

[ Name ]:
DENV-IN-8

Biological Activity

[Description]:

DENV-IN-8 (Compound 5e) is a DENV2 inhibitor with an EC50 of 0.068 μM[1].

[Related Catalog]:

Research Areas >> Infection

[Target]

EC50: 0.068 μM (DENV2)[1]


[In Vitro]

DENV-IN-8 (Compound 5e) (72 h) 对 DENV2 感染的 LLC/MK2 细胞具有抗登革热活性，EC50 为 0.068 ± 0.040 μM，对正常细胞具有低毒性[1]。

[References]

[1]. Patigo A, et al. Design, synthesis, in vitro, in silico, and SAR studies of flavone analogs towards anti-dengue activity. Sci Rep. 2022 Dec 14;12(1):21646.  

Chemical & Physical Properties

[ Molecular Formula ]:
C21H18O7

[ Molecular Weight ]:
382.36

Related Compounds