3-(diethylamino)propyl 3-phenylbicyclo[2.2.1]heptane-3-carboxylate
Names
[ CAS No. ]:
20448-86-6
[ Name ]:
3-(diethylamino)propyl 3-phenylbicyclo[2.2.1]heptane-3-carboxylate
[Synonym ]:
Bornaprinum [INN-Latin]
Bornaprine
2-Norbornanecarboxylic acid,2-phenyl-,3-(diethylamino)propyl ester
Sormodren
Kr 339
KR 339 [German]
2-Phenylbicyclo(2.2.1)heptane-2-carboxylic acid,3-(diethylamino)propyl ester
Bornaprino [INN-Spanish]
Chemical & Physical Properties
[ Density]:
1.056g/cm3
[ Boiling Point ]:
434.3ºC at 760mmHg
[ Molecular Formula ]:
C21H31NO2
[ Molecular Weight ]:
329.47600
[ Exact Mass ]:
329.23500
[ PSA ]:
29.54000
[ LogP ]:
4.01950
[ Vapour Pressure ]:
9.6E-08mmHg at 25°C
[ Index of Refraction ]:
1.535
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DT4750000
- CHEMICAL NAME :
- Bicyclo(2.2.1)heptane-2-carboxylic acid, 2-phenyl-, 3-(diethylamino)propyl ester
- CAS REGISTRY NUMBER :
- 20448-86-6
- LAST UPDATED :
- 199203
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C21-H31-N-O2
- MOLECULAR WEIGHT :
- 329.53
- WISWESSER LINE NOTATION :
- L55 ATJ CVO3N2&2 CR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 112 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 128,204,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 26 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 128,204,1960