(2R,3R)-2-chloro-3-methyloxirane
Names
[ CAS No. ]:
21947-76-2
[ Name ]:
(2R,3R)-2-chloro-3-methyloxirane
[Synonym ]:
Propane,1-chloro-1,2-epoxy-,(E)
trans-1-Chloro-1,2-epoxypropane
trans-2-Chloro-3-methyloxirane
trans-1-Chloropropene oxide
trans-Cpo
Chemical & Physical Properties
[ Molecular Formula ]:
C3H5ClO
[ Molecular Weight ]:
92.52420
[ Exact Mass ]:
92.00290
[ PSA ]:
12.53000
[ LogP ]:
0.97000
[ Vapour Pressure ]:
61.1mmHg at 25°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TX4850000
- CHEMICAL NAME :
- Propane, 1-chloro-1,2-epoxy-, (E)-
- CAS REGISTRY NUMBER :
- 21947-76-2
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C3-H5-Cl-O
- MOLECULAR WEIGHT :
- 92.53
- WISWESSER LINE NOTATION :
- T3OTJ BG C1 -T
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 400 mg/kg/73W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 40 mg/kg/60W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application
MUTATION DATA
- TYPE OF TEST :
- Morphological transformation
- TEST SYSTEM :
- Rodent - hamster Embryo
- DOSE/DURATION :
- 550 umol/L
- REFERENCE :
- JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 69,531,1982