β-Glucuronide-dPBD-PEG5-NH2
Names
[ CAS No. ]:
2246363-68-6
[ Name ]:
β-Glucuronide-dPBD-PEG5-NH2
Biological Activity
[Description]:
β-Glucuronide-dPBD-PEG5-NH2 is the β-glucuronide-linked pyrrolobenzodiazepine dimer, which binds to the prenylated antibody for synthesis of antibody-drug conjugate (ADC) cIRCR201-dPBD. β-glucuronide-linkage as a cleavable linker. β-Glucuronide-dPBD-PEG5-NH2, as a prodrug of cIRCR201-dPBD, reduces side effects[1].
[Related Catalog]:
[Target]
Drug-linker conjugates for ADC, Apoptosis[1]
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C78H101N7O35
[ Molecular Weight ]:
1696.66