Microtubule inhibitor 1

Names

[ CAS No. ]:
2305668-80-6

[ Name ]:
Microtubule inhibitor 1

Biological Activity

[Description]:

Microtubule inhibitor 1 is an antitumor agent with microtubule polymerization inhibitory activity, with an IC50 value of 9-16 nM in cancer cells[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin
Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin

[Target]

Microtubule polymerization[1].


[References]

[1]. Li W, et al. Discovery of Novel Quinoline-Chalcone Derivatives as Potent Antitumor Agents with Microtubule Polymerization Inhibitory Activity. J Med Chem. 2019 Jan 24;62(2):993-1013.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H19NO3

[ Molecular Weight ]:
333.38

Related Compounds