EC33

Names

[ CAS No. ]:
232261-88-0

[ Name ]:
EC33

[Synonym ]:
(3S)-3-Amino-4-sulfanyl-1-butanesulfonic acid
1-Butanesulfonic acid, 3-amino-4-mercapto-, (3S)-

Biological Activity

[Description]:

EC33 is a selective aminopeptidase A (APA) inhibitor. EC33 blocks the pressor response of exogenous Ang II. EC33 does not cross the blood-brain barrier. EC33 has the potential for salt-dependent model of hypertension research[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> Metabolic Enzyme/Protease >> Aminopeptidase

[References]

[1]. Laurence Bodineau, et al. Orally active aminopeptidase A inhibitors reduce blood pressure: a new strategy for treating hypertension. Hypertension. 2008 May;51(5):1318-25.  

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C4H11NO3S2

[ Molecular Weight ]:
185.265

[ Exact Mass ]:
185.018036

[ LogP ]:
-1.48

[ Index of Refraction ]:
1.559

Related Compounds