Cdc7-IN-18

Names

[ CAS No. ]:
2562329-14-8

[ Name ]:
Cdc7-IN-18

Biological Activity

[Description]:

Cdc7-IN-18 (compound 1-2) is a potent CDC7 inhibitor with an IC50 of 1.29 nM for Cdc7/DBF4 enzyme. Cdc7-IN-18 shows antiproliferative activities with IC50 of 53.62 nM in COLO205 cells[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> CDK

[Target]

Cdc7:1.29 nM (IC50)


[References]

[1]. Li Gang, et al. Tetracyclic compounds as cdc7 inhibitors. WO2020239107A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C19H21N5OS

[ Molecular Weight ]:
367.47

Related Compounds