l-alanine (u-13c3; 15n)

Names

[ Name ]:
l-alanine (u-13c3; 15n)

[Synonym ]:
MFCD00144541
Alanine-C-N
(C,N)Alanine

Biological Activity

[Description]:

L-Alanine-13C2,15N is the 13C- and 15N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Nagashima T, et al. Selective Elimination of Human Induced Pluripotent Stem Cells Using Medium with High Concentration of L-Alanine. Sci Rep. 2018 Aug 20;8(1):12427.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Melting Point ]:
314.5ºC (dec.)(lit.)

[ Molecular Formula ]:
C₁₃C₂H₇₁₅NO₂

[ Molecular Weight ]:
92.07

[ Exact Mass ]:
93.054779

[ PSA ]:
63.32000

[ LogP ]:
0.11850

[ Index of Refraction ]:
1.460

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3