4-[aziridin-1-yl-[4-[aziridin-1-yl(morpholin-4-yl)phosphoryl]oxyphenoxy]phosphoryl]morpholine
Names
[ CAS No. ]:
34180-22-8
[ Name ]:
4-[aziridin-1-yl-[4-[aziridin-1-yl(morpholin-4-yl)phosphoryl]oxyphenoxy]phosphoryl]morpholine
[Synonym ]:
a-195
Chemical & Physical Properties
[ Density]:
1.46g/cm3
[ Boiling Point ]:
585.1ºC at 760 mmHg
[ Molecular Formula ]:
C18H28N4O6P2
[ Molecular Weight ]:
458.38600
[ Flash Point ]:
307.7ºC
[ Exact Mass ]:
458.14800
[ PSA ]:
103.18000
[ LogP ]:
1.70760
[ Index of Refraction ]:
1.623
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SZ4150000
- CHEMICAL NAME :
- Phosphinic acid, (1-aziridinyl)morpholino-, p-phenylene ester
- CAS REGISTRY NUMBER :
- 34180-22-8
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C18-H28-N4-O6-P2
- MOLECULAR WEIGHT :
- 458.44
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 130 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- FATOBP Farmakologiya i Toksikologiya (Kiev). Pharmacology and Toxicology. (Kievskii Nauchno- Issledovatel'skii Institut Farmakologii i Toksikologii, Kiev, USSR) No.1- 1964- Volume(issue)/page/year: 6,145,1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 265 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- FATOBP Farmakologiya i Toksikologiya (Kiev). Pharmacology and Toxicology. (Kievskii Nauchno- Issledovatel'skii Institut Farmakologii i Toksikologii, Kiev, USSR) No.1- 1964- Volume(issue)/page/year: 6,145,1971
Safety Information
[ HS Code ]:
2934999090
Customs
[ HS Code ]: 2934999090
[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%