Prenyl-IN-1

Names

[ CAS No. ]:
360561-53-1

[ Name ]:
Prenyl-IN-1

Biological Activity

[Description]:

Prenyl-IN-1 is a protein prenylation inhibitor, especially a geranylgeranyltransferase (GGT) or a farnesyltransferase (FT) inhibitor, exhibiting potent activity against oxidative stress, and particularly in the treatment of Parkinson's Disease.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Farnesyl Transferase
Research Areas >> Neurological Disease

[References]

[1]. Compounds which inhibits protein prenylation e.g. geranylgeranyltransferase or farnesyltransferase inhibitors for treating parkinson's disease. WO2006051423A1


[Related Small Molecules]

Tipifarnib (R115777) | FTI-277 (hydrochloride) | L-778123 (hydrochloride) | Lonafarnib | BMS 214662 | FTI-276 trifluoroacetate salt | LNK754 | RPR107393 free base | YM-53601 free base

Chemical & Physical Properties

[ Molecular Formula ]:
C28H24ClN5O2

[ Molecular Weight ]:
497.98

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds