diphenoxylate hydrochloride
Names
[ CAS No. ]:
3810-80-8
[ Name ]:
diphenoxylate hydrochloride
[Synonym ]:
Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylate hydrochloride (1:1)
DIPHENOXYLATE HYDROCHLORIDE
ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylate hydrochloride
4-Piperidinecarboxylic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester, hydrochloride (1:1)
DIPHENOXYLATE HYDROCHLORIDE ANTIPERISTAL TIC,ANTI
Ethyl-1-(3-cyan-3,3-diphenylpropyl)-4-phenylpiperidin-4-carboxylathydrochlorid
DIPHENOXYLATE HCL
Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-4-piperidinecarboxylate hydrochloride (1:1)
1-(3-Cyano-3,3-diphenylpropyl)-4-phenyl-4-piperidinecarboxylic Acid Ethyl Ester Monohydrochloride
1-(3-cyano-3,3-diphénylpropyl)-4-phénylpipéridine-4-carboxylate d'éthyle chlorhydrate
r1132
4-Ethoxycarbonyl-α,α,4-triphenyl-1-piperidinebutyronitrile, hydrochloride
Chemical & Physical Properties
[ Boiling Point ]:
602.3ºC at 760mmHg
[ Melting Point ]:
220.0-222.5ºC
[ Molecular Formula ]:
C30H33ClN2O2
[ Molecular Weight ]:
489.048
[ Flash Point ]:
318ºC
[ Exact Mass ]:
488.223053
[ PSA ]:
53.33000
[ LogP ]:
6.22318
[ Water Solubility ]:
Very slightly soluble in water, freely soluble in methylene chloride, sparingly soluble in ethanol (96 per cent).
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NS5300000
- CHEMICAL NAME :
- Isonipecotic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester, hydrochloride
- CAS REGISTRY NUMBER :
- 3810-80-8
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C30-H32-N2-O2.Cl-H
- MOLECULAR WEIGHT :
- 489.10
- WISWESSER LINE NOTATION :
- T6NTJ A2XR&R&CN DVO2 DR &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 221 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,1633,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >320 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,1636,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >160 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,1636,1974 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3182 No. of Facilities: 105 (estimated) No. of Industries: 1 No. of Occupations: 4 No. of Employees: 8242 (estimated) No. of Female Employees: 7235 (estimated)
Safety Information
[ RIDADR ]:
UN 1544
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)