Bis-propargyl-PEG6

Names

[ CAS No. ]:
400775-35-1

[ Name ]:
Bis-propargyl-PEG6

[Synonym ]:
4,7,10,13,16,19,22-Heptaoxapentacosa-1,24-diyne
Bis-propargyl-PEG6

Biological Activity

[Description]:

Bis-propargyl-PEG6 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG6 can be used to synthesize the polymer linked multimers of guanosine-3', 5'-cyclic monophosphates[1].

[Related Catalog]:

Research Areas >> Metabolic Disease
Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs


[In Vitro]

Bis-propargyl-PEG6 can be used to synthesize the polymer linked multimers of guanosine-3', 5'-cyclic monophosphates which can be used as reagents for signal transduction research and as modulators of cyclic nucleotide-regulated binding proteins and isoenzymes thereof, and as ligands for affinity chromatography, for antibody production or for diagnostic applications e.g. on chip surfaces[1].

[References]

[1]. Hans-Gottfried Genieser, et al. New polymer linked multimers of guanosine-3', 5'-cyclic monophosphates. WO2018041942A1.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
421.9±40.0 °C at 760 mmHg

[ Molecular Formula ]:
C18H30O7

[ Molecular Weight ]:
358.427

[ Flash Point ]:
162.5±27.2 °C

[ Exact Mass ]:
358.199158

[ LogP ]:
-1.13

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.465

[ Storage condition ]:
2-8°C

Related Compounds