5-Bromo-3’-deoxy-3’-fluorouridine

Names

[ CAS No. ]:
439579-22-3

[ Name ]:
5-Bromo-3’-deoxy-3’-fluorouridine

[Synonym ]:
5-Bromo-3'-deoxy-3'-fluorouridine
MFCD25542530
Uridine, 5-bromo-3'-deoxy-3'-fluoro-

Biological Activity

[Description]:

5-Bromo-3’-deoxy-3’-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Density]:
2.0±0.1 g/cm3

[ Molecular Formula ]:
C9H10BrFN2O5

[ Molecular Weight ]:
325.09

[ Exact Mass ]:
323.975708

[ LogP ]:
-0.45

[ Index of Refraction ]:
1.648

Related Compounds