(2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]-3-methylbutanoic acid
Names
[ CAS No. ]:
68352-97-6
[ Name ]:
(2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]-3-methylbutanoic acid
[Synonym ]:
N-(4-(((2,4-Diamino-6-pteridinyl)methyl)methylamino)benzoyl)-DL-valine
N-(p-(((2,4-Diamino-6-pteridinyl)methyl)methylamino)benzoyl)valine
Valine,N-(p-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-,DL
DL-Valine,N-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)
Chemical & Physical Properties
[ Molecular Formula ]:
C20H24N8O3
[ Molecular Weight ]:
424.45600
[ Exact Mass ]:
424.19700
[ PSA ]:
173.97000
[ LogP ]:
1.96180
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YV9392200
- CHEMICAL NAME :
- Valine, N-(p-(((2,4-diamino-6-pteridinyl)methyl)methylamino)b enzoyl)-, DL-
- CAS REGISTRY NUMBER :
- 68352-97-6
- LAST UPDATED :
- 199610
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C20-H24-N8-O3
- MOLECULAR WEIGHT :
- 424.52
- WISWESSER LINE NOTATION :
- T66 BN DN GN JNJ CZ EZ H1N1&R D1MYVQY1&1 -DL
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NEOLA4 Neoplasma. (Karger-Libri, P.O. Box, CH-4009 Basel, Switzerland) V.4- 1957- Volume(issue)/page/year: 29,43,1982